产品货号：
Z38929
中文名称：
SHP2/PTPN11 (Ab-542)抗体
英文名称：
Anti-SHP2/PTPN11 (Ab-542) Antibody (Clone#OTI3F2)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SHP2/PTPN11 (Ab-542) Antibody (Clone#OTI3F2) |
| 指标别名 | BPTP3;CFC;NS1;PTP 1D;PTP 2C;PTP2C;PTPN11;SH PTP2;SH PTP3;SHP 2;SHP2;SHPTP2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat,dog |
| 应用范围 | WB,FCM |
| 基因名称 | PTPN11 |
| 克隆号 | OTI3F2 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Full length human recombinant protein of human PTPN11(NP_002825) produced in HEK293T cell. |
| 实际分子量 | 67.8KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | PTPN11 (Tyrosine-protein phosphatase non-receptor type 11),also known as protein-tyrosine phosphatase 1D (PTP-1D),protein-tyrosine phosphatase 2C (PTP-2C),TYROSINE PHOSPHATASE SHP2 (SHP2),BPTP3,SH-PTP2,SHP-2,SH-PTP3,is an enzyme that in humans is encoded by the PTPN11 gene.PTPN11 is a member of the protein tyrosine phosphatase (PTP) family.The open reading frame consists of 1,779 nucleotides potentially encoding a protein of 593 amino acids with a predicted molecular mass of 68kD.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,differentiation,mitotic cycle,and oncogenic transformation.This PTP contains two tandem Src homology-2 domains,which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates.This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions,such as mitogenic activation,metabolic control,transcription regulation,and cell migration.Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. |
| Uniprot ID | Q06124 |
| 基因名全称 | protein tyrosine phosphatase,non-receptor type 11 |
| 蛋白名全称 | Tyrosine-protein phosphatase non-receptor type 11 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Flow cytometry (FCM) 1:100 |
相关搜索：SHP2/PTPN11 (Ab-542)抗体，SHP2抗体，PTPN11 (Ab-542)单抗，Anti-SHP2/PTPN11 (Ab-542) Antibody (Clone#OTI3F2)